Science deals with the realm of Effects. Spirituality goes to the Causes...
No amount of scientific "investigation" will ever penetrate to the Causes - because Cause cannot be "found", it can only be experienced in Subjective Reality.
It's like Integration - where you try to find the area of a curve and use rectangles with infinitesimally smaller widths to "approximate" the total area...
Science is like this rectangle approach - can only "approximate" Truth - 95%, 99%, 99.99%, 99.9999999% but never the actual 100% Truth...
It's by nature - science tries to arrive at Objective "approximations" of Truth, which is 100% Subjective. Would recommend The Eye Of The I on this list to dive deeper into all this